Focusing in on T Cell Cross-Reactivity
نویسندگان
چکیده
To provide broad immunity to a vast array of foreign antigens with a limited number of T lymphocytes, each cell has to recognize many targets. By implementing a strategy to identify T cell receptor (TCR) ligands and investigating at a fine granularity their structure and sequence relationship, Birnbaum et al. demonstrate the surprisingly tight focus of such T cell cross-reactivity.
منابع مشابه
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عنوان ژورنال:
- Cell
دوره 157 شماره
صفحات -
تاریخ انتشار 2014